I used to be an Opera Fanboy. But these days I find myself using Firefox on Linux. Plus Chrome and Safari each have their own plusses. So I guess it is totally a fersonal choice.
My Order of prefence runs:
1. Opera [Features Overload]
2. Firefox [Has some really cool addons]
3. IE 8 [Yes its on my list! its not that bad you know.]
4. Chrome [For the huge screen space. Doesn't implement many up-comming CSS functions and properties though.]
5. Safari [Awesome Fonts. Period]
6. Lynx [Surfing in a text brower is *just* something else
]